Progesterone – Is it right for me?

Progesterone can be very helpful for some people, but it isn’t the best choice for everyone. Your provider will review your history and decide if it fits safely into your plan.

Do not use progesterone if you:

• Are pregnant, breastfeeding, or planning pregnancy

• Are allergic or sensitive to progesterone

• Have ever had blood clots or clotting disorders

• Have (or have had) breast, ovarian, cervical, or endometrial cancer

• Have significant liver disease

• Have had a missed or ectopic pregnancy

• Have unexplained vaginal bleeding that hasn’t been evaluated

• Have a history of stroke or reduced blood flow to the brain

• Have had a heart attack or active coronary artery disease with chest pain/angina

• Have uncontrolled major depression or other uncontrolled psychiatric conditions

• Have dementia or another significant neurological disorder

Tell your provider before starting if you have:

• Family history of breast or genital cancers

• Family history of blood clots or known clotting disorders

• Depression that isn’t well treated or stable

• Endometriosis, diabetes, high blood pressure, kidney disease, or bone/bone density issues

• Systemic lupus erythematosus (SLE), migraines, asthma, or epilepsy

• A history of smoking

Medicines & procedures

• If you take warfarin or other blood thinners, your dose may need adjustment while on progesterone

• Your provider may have you stop progesterone before major surgery or during periods of prolonged immobility

Stop progesterone and contact your provider if you notice:

• Yellowing of the skin or eyes

• New or worsening vision changes

• Signs of a clot (leg pain/swelling, chest pain, sudden shortness of breath)

• A migraine that is unusually severe

• A big increase in blood pressure

• Severe depression or major mood changes

This information is for education only and doesn’t replace medical advice. Your provider is the best person to decide if progesterone belongs in your ongoing treatment plan.

Latanoprost is used topically in small, targeted amounts to support fuller-looking density. Most people tolerate it well.

With topical use, some people may notice:

• Mild itching or irritation where it’s applied

• Slight redness or darkening of the skin in the application area

Because Latanoprost was originally developed for the eye area, it’s important to:

• Keep it away from the eyes and eyelashes

• Let your provider know if you have significant eye conditions or any new eye symptoms

If anything feels uncomfortable or doesn’t settle—such as persistent irritation or changes you’re unsure about—reach out to your care team. Latanoprost can always be reduced or removed as part of your ongoing, personalized plan.

With topical use, some people may notice:

• Mild redness or warmth

• Temporary dryness, peeling, or flaking

These effects are common early on and often improve as your skin gets used to the product. If the area feels very irritated or looks overly red, you can use your formula less often and reach out to your provider so your plan can be adjusted.

A few key points:

• Avoid use during pregnancy or while breastfeeding

• Keep out of reach of children

• Avoid applying to sunburned, very irritated, or eczematous skin

• Keep away from the eyes, mouth, and other mucous membranes

• It’s helpful to protect treated areas from excessive sun exposure

If anything feels unusually uncomfortable or doesn’t settle, let your care team know—retinoic acid can always be reduced or removed as part of your ongoing, personalized formula.

Niacinamide is generally very well tolerated on the skin, which is why it’s a staple in our formulas.

With topical use, a small number of people may notice:

• Mild redness

• Itching

• A slight burning or warming sensation

These are usually temporary and improve as your skin or scalp adjusts. If anything feels very uncomfortable, looks overly red, or you notice a rash, stop using the product on that area and let your provider know so your formula can be adjusted.

Because niacinamide can also be taken by mouth in other products or supplements, always share your full medication and supplement list with your care team. That helps us keep your routine simple, safe, and easy to stay consistent with over time.

Most people do well on spironolactone when it’s used thoughtfully and monitored over time. Some may notice:

• Lowered blood pressure, dizziness, or feeling lightheaded

• More frequent urination

• Headaches

• Breast tenderness or enlargement

• Irregular or missed periods

• Mild changes in hair texture or color

• A distinct smell with some topical preparations

Because spironolactone can affect fluid and electrolyte balance, let your provider know if you have kidney problems, heart disease, adrenal or electrolyte issues, or a history of breast or other hormone-sensitive cancers. It should not be used if you are pregnant, planning pregnancy, or breastfeeding.

Spironolactone can interact with other medications and supplements, so always share your full medication list with your care team. Our goal is to make it part of a safe, ongoing plan that can be adjusted as your hair and health needs evolve.